Rockwood K, Kirkland S, Hogan DB, Macknight C, Merry H, Verreault R, Wolfson C, McDowell I. Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people. Arch Neurol. 2002 Feb;59(2):223-7. PubMed.

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  1. This paper provides further support for the observation that use of statins is associated with a lower risk of AD. Specifically, this paper reduces the possibility that the negative correlation between statin use and AD is due to the a spurious outcome of doctor prescribing characteristics, rather than a real action of statins on some aspect of the pathophysiology of AD.

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    • User Profile Image John Hardy
      Institute of Neurology, UCL
    • Posted:

    Together these papers (Locatelli et al., Okamura et al., and Rockwood et al.) further the interesting link between cholesterol metabolism and AD

    View all comments by John Hardy

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