Yeh FL, Hansen DV, Sheng M. TREM2, Microglia, and Neurodegenerative Diseases. Trends Mol Med. 2017 Jun;23(6):512-533. Epub 2017 Apr 22 PubMed.

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Research Models

  1. Trem2 T66M KI
  2. Trem2 KO (JAX)
  3. Trem2 KO (KOMP) x APPPS1
  4. Trem2 KO (KOMP)
  5. Trem2 KO (KOMP) x htau
  6. Trem2 KO (Colonna)
  7. Trem2 KO (Colonna) x 5XFAD
  8. Trem2 KO (Colonna) x PS19
  9. TREM2-BAC
  10. TREM2-BAC X 5xFAD