Kaufman SK, Del Tredici K, Thomas TL, Braak H, Diamond MI. Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer's disease and PART. Acta Neuropathol. 2018 Jul;136(1):57-67. Epub 2018 May 11 PubMed.
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China National Clinical Research Centre for Neurological Diseases，Beijing Tiantan Hospital, CMU
Interesting. If tau seeding activity begins in the transentorhinal/entorhinal regions rather than locus coerulues in Alzheimer’s disease or PART, where do tau oligomers in transentorhinal/entorhinal regions come from?
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