Guo Q, Fu W, Holtsberg FW, Steiner SM, Mattson MP.
Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations.
J Neurosci Res. 1999 Jun 1;56(5):457-70.
PubMed.
This suggests superoxide production by PS-1 mutations. What remains to be seen is the relationship between radical species and amyloidgenesis, both of which were caused by PS-1.
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Osaka City University Medical School
This suggests superoxide production by PS-1 mutations. What remains to be seen is the relationship between radical species and amyloidgenesis, both of which were caused by PS-1.
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