Varnum MM, Clayton KA, Yoshii-Kitahara A, Yonemoto G, Koro L, Ikezu S, Ikezu T. A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells. J Biol Chem. 2017 Jun 23;292(25):10651-10663. Epub 2017 May 10 PubMed.

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Mutations

  1. TREM2 T66M
  2. TREM2 S116C