Martin ER, Lai EH, Gilbert JR, Rogala AR, Afshari AJ, Riley J, Finch KL, Stevens JF, Livak KJ, Slotterbeck BD, Slifer SH, Warren LL, Conneally PM, Schmechel DE, Purvis I, Pericak-Vance MA, Roses AD, Vance JM. SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease. Am J Hum Genet. 2000 Aug;67(2):383-94. PubMed.

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    • User Profile Image John Hardy
      Institute of Neurology, UCL
    • Posted:

    Can we use SNP's and CHIP's to find genes which lead to complex diseases including late onset AD: this important paper illustrates it will be extraordinarily difficult or perhaps impossible.

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  2. New associations between ApoE and AD

    View all comments by Benjamin Wolozin

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