Zheng-Fischhöfer Q, Biernat J, Mandelkow EM, Illenberger S, Godemann R, Mandelkow E. Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation. Eur J Biochem. 1998 Mar 15;252(3):542-52. PubMed.

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    • User Profile Image Hiroshi Mori
      Osaka City University Medical School
    • Posted:

    We need the detailed phosphorylation mechanism of tau to understand cell death. This is but one tau study, but is a step towards knowing the molecular mechanism of dementia.

    View all comments by Hiroshi Mori

  2. We need the detailed phosphorylation mechanism of tau to understand cell death. This is but one tau study, but is a step towards knowing the molecular mechanism of dementia.

    View all comments by Peter Davies

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