Williamson TG, Mok SS, Henry A, Cappai R, Lander AD, Nurcombe V, Beyreuther K, Masters CL, Small DH. Secreted glypican binds to the amyloid precursor protein of Alzheimer's disease (APP) and inhibits APP-induced neurite outgrowth. J Biol Chem. 1996 Dec 6;271(49):31215-21. PubMed.
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Alzheimer's & Dementia
This paper is important because it provides further evidence for the neuroprotective role of APP. Mechanisms of neurite outgrowth are important areas of research in developing treatments for AD.
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