Jiang T, Tan L, Chen Q, Tan MS, Zhou JS, Zhu XC, Lu H, Wang HF, Zhang YD, Yu JT. A rare coding variant in TREM2 increases risk for Alzheimer's disease in Han Chinese. Neurobiol Aging. 2016 Jun;42:217.e1-3. Epub 2016 Mar 3 PubMed.

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This paper appears in the following:

Mutations

  1. TREM2 H157Y
  2. TREM2 S183C
  3. TREM2 A192T
  4. TREM2 W200C

News

  1. New Evidence Confirms TREM2 Binds Aβ, Drives Protective Response
  2. TREM2 Cleavage Site Pinpointed: A Gateway to New Therapies?
  3. Cut Loose, Soluble TREM2 Beckons Microglia to Mop Up Plaques

Research Models

  1. Trem2-H157Y knock-in
  2. TREM2-sol
  3. TREM2-IPD
  4. AAV-sTREM2 5xFAD
  5. Trem2-H157Y x 5xFAD