Siman R, Reaume AG, Savage MJ, Trusko S, Lin YG, Scott RW, Flood DG. Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability. J Neurosci. 2000 Dec 1;20(23):8717-26. PubMed.

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Comments

  1. Important clarification in an ongoing debate.

    View all comments by Benjamin Wolozin

  2. Very interesting knock-in transgenic mice models where neither APP nor PS were overexpressed.

    View all comments by Edward Koo

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Research Models

  1. PS1 P264L