Brickman AM, Manly JJ, Honig LS, Sanchez D, Reyes-Dumeyer D, Lantigua RA, Lao PJ, Stern Y, Vonsattel JP, Teich AF, Airey DC, Proctor NK, Dage JL, Mayeux R. Plasma p-tau181, p-tau217, and other blood-based Alzheimer's disease biomarkers in a multi-ethnic, community study. Alzheimers Dement. 2021 Feb 13; PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
tau-p181
(Plasma)		 AD
(131)		 1.24 ± 1.09
pg/mL		 Electrochemiluminescence;
Other/Not Specified;
Meso Scale Discovery		 McKhann et al., 2011
tau-p181
(Plasma)		 CTRL-
CNC
(169)		 0.86 ± 0.73
pg/mL		 Electrochemiluminescence;
Other/Not Specified;
Meso Scale Discovery
tau-p217
(Plasma)		 AD
(131)		 0.32 ± 0.32
pg/mL		 Electrochemiluminescence;
Other/Not Specified;
Meso Scale Discovery		 McKhann et al., 2011
tau-p217
(Plasma)		 CTRL-
CNC
(169)		 0.18 ± 0.17
pg/mL		 Electrochemiluminescence;
Other/Not Specified;
Meso Scale Discovery
tau-total
(Plasma)		 AD
(131)		 4.9 ± 2.06
pg/mL		 SIMOA;
Neuro 3-plex A;
Quanterix		 McKhann et al., 2011
tau-total
(Plasma)		 CTRL-
CNC
(169)		 4.94 ± 2.13
pg/mL		 SIMOA;
Neuro 3-plex A;
Quanterix

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This paper appears in the following:

AlzBiomarker

  1. AD vs CTRL : tau-p181 (Plasma and Serum)
  2. CTRL vs AD : tau-p181 (Plasma and Serum)
  3. AD vs CTRL : tau-p217 (Plasma and Serum)
  4. CTRL vs AD : tau-p217 (Plasma and Serum)
  5. AD vs CTRL : tau-total (Plasma and Serum)
  6. CTRL vs AD : tau-total (Plasma and Serum)