Mayeux R, Honig LS, Tang MX, Manly J, Stern Y, Schupf N, Mehta PD. Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: relation to age, mortality, and risk. Neurology. 2003 Nov 11;61(9):1185-90. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ40 (Plasma and Serum)
- CTRL vs AD : Aβ40 (Plasma and Serum)
- AD vs CTRL : Aβ42 (Plasma and Serum)
- CTRL vs AD : Aβ42 (Plasma and Serum)
Curated Study Data
Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
---|---|---|---|---|
Aβ40 (Plasma) |
AD (79) |
153.6 ± 46.7 pg/mL |
ELISA; Other/Not Specified; In-house |
McKhann et al., 1984 |
Aβ40 (Plasma) |
CTRL- CNC (365) |
133.3 ± 61.9 pg/mL |
ELISA; Other/Not Specified; In-house |
|
Aβ42 (Plasma) |
AD (79) |
68.7 ± 24.2 pg/mL |
ELISA; Other/Not Specified; In-house |
McKhann et al., 1984 |
Aβ42 (Plasma) |
CTRL- CNC (365) |
58.8 ± 32.9 pg/mL |
ELISA; Other/Not Specified; In-house |
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