Hamdane M, Smet C, Sambo AV, Leroy A, Wieruszeski JM, Delobel P, Maurage CA, Ghestem A, Wintjens R, Bégard S, Sergeant N, Delacourte A, Horvath D, Landrieu I, Lippens G, Buée L. Pin1: a therapeutic target in Alzheimer neurodegeneration. J Mol Neurosci. 2002 Dec;19(3):275-87. PubMed.

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Comments

  1. This work is a nice adjunct to the Bioessays review by Lu et al (Feb 2003). Animal models of altered pin1 levels/function are essential for assessing the role of pin1 in neurodegeneration, and its potenital as a therapeutic target.

    References:

    Lu KP, Liou YC, Vincent I. Proline-directed phosphorylation and isomerization in mitotic regulation and in Alzheimer's Disease. Bioessays. 2003 Feb;25(2):174-81. PubMed.

    View all comments by Inez Vincent

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