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McLaurin J, Franklin T, Chakrabartty A, Fraser PE. Phosphatidylinositol and inositol involvement in Alzheimer amyloid-beta fibril growth and arrest. J Mol Biol. 1998 Apr 24;278(1):183-94. PubMed. Recommends Please login to recommend the paper. Comments Hiroshi Mori Osaka City University Medical School Posted: 21 May 2002 At neutral pH, PI influences amyloidosis of in vitro Ab1-42 but not Ab1-40. This may be relevant with the presence of diffuse plaque formation. View all comments by Hiroshi Mori Nikolaos K. Robakis Mount Sinai School of Medicine, NYU Posted: 21 May 2002 This is a nice paper because it examines the role of lipids in amyloid formation. Such a role was already indicated by several laboratories. There are good evidence indications that the first seeds of amyloid fibrils may form on membranes. View all comments by Nikolaos K. Robakis Make a Comment To make a comment you must login or register.
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Osaka City University Medical School
At neutral pH, PI influences amyloidosis of in vitro Ab1-42 but not Ab1-40. This may be relevant with the presence of diffuse plaque formation.
Mount Sinai School of Medicine, NYU
This is a nice paper because it examines the role of lipids in amyloid formation. Such a role was already indicated by several laboratories. There are good evidence indications that the first seeds of amyloid fibrils may form on membranes.
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