Schupf N, Tang MX, Fukuyama H, Manly J, Andrews H, Mehta P, Ravetch J, Mayeux R. Peripheral Abeta subspecies as risk biomarkers of Alzheimer's disease. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14052-7. Epub 2008 Sep 8 PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ40 (Plasma and Serum)
- CTRL vs AD : Aβ40 (Plasma and Serum)
- AD vs CTRL : Aβ42 (Plasma and Serum)
- CTRL vs AD : Aβ42 (Plasma and Serum)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ40 (Plasma) |
AD (104) |
128.8 ± 4.5† pg/mL |
ELISA; Other/Not Specified; In-house |
McKhann et al., 1984 |
| Aβ40 (Plasma) |
CTRL- CNC (1021) |
120.3 ± 1.6† pg/mL |
ELISA; Other/Not Specified; In-house |
|
| Aβ42 (Plasma) |
AD (104) |
47.9 ± 2† pg/mL |
ELISA; Other/Not Specified; In-house |
McKhann et al., 1984 |
| Aβ42 (Plasma) |
CTRL- CNC (1021) |
48.2 ± 0.7† pg/mL |
ELISA; Other/Not Specified; In-house |
† Mean ± SEM
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