Rosengren LE, Karlsson JE, Karlsson JO, Persson LI, Wikkelsø C. Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF. J Neurochem. 1996 Nov;67(5):2013-8. PubMed.
AlzBiomarker Database
Meta-Analysis
Curated Study Data
Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
---|---|---|---|---|
NFL (CSF) |
AD (11) |
346 ± 176 pg/mL |
ELISA; Other/Not Specified; In-house |
McKhann et al., 1984 |
NFL (CSF) |
ALS (12) |
1743 ± 1661 pg/mL |
ELISA; Other/Not Specified; In-house |
Brooks, 1994 |
NFL (CSF) |
CTRL- CNC (34) |
138 ± 31 pg/mL |
ELISA; Other/Not Specified; In-house |
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