Sasmita AO, Ong EC, Nazarenko T, Mao S, Komarek L, Thalmann M, Hantakova V, Spieth L, Berghoff SA, Barr HJ, Hingerl M, Börensen F, Hirrlinger J, Simons M, Stevens B, Depp C, Nave KA. Parental origin of transgene modulates amyloid-β plaque burden in the 5xFAD mouse model of Alzheimer's disease. Neuron. 2025 Jan 20; Epub 2025 Jan 20 PubMed.

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Research Models

  1. mThy1-hAPP751 (TASD41)
  2. TMHT (Thy-1 mutated human tau)
  3. Tg-SwDI (APP-Swedish,Dutch,Iowa)
  4. 5xFAD (B6SJL)
  5. 3xTg
  6. APPSwDI x NOS2 Knock-out
  7. THY-Tau22
  8. APP(V717I)
  9. Tau P301L
  10. APP(V717I) x PS1(A246E)
  11. Tg-ArcSwe
  12. APPDutch
  13. APPPS1
  14. tg-APPSwe
  15. TauPS2APP
  16. APPSwe
  17. Human-BACE1
  18. APP23
  19. APP751SL/PS1 KI
  20. hBACE54
  21. PS1(A246E)
  22. PS2APP
  23. PS2APP (PS2(N141I) x APPswe)
  24. Tg4-42
  25. TBA42
  26. hTau.P301S
  27. TAS10 (thy1-APPswe)
  28. TPM (Thy-1 PS1.M146V)
  29. TASTPM (TAS10 x TPM)
  30. ARTE10
  31. mThy-1 3R Tau (line 13)
  32. APP23 x PS1-R278I
  33. A7 APP transgenic
  34. Tau4RTg2652
  35. hTau-AT (hTau40-AT)
  36. 5xFAD (C57BL6)
  37. AD-BXD
  38. PA-Rab5
  39. TgDimer