Lindsten K, de Vrij FM, Verhoef LG, Fischer DF, Van Leeuwen FW, Hol EM, Masucci MG, Dantuma NP. Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation. J Cell Biol. 2002 Apr 29;157(3):417-27. PubMed.

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  1. More evidence that the +1 mutations causes cell dysfunction.

    View all comments by Edward Koo

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