Peng Q, Lao X, Huang X, Qin X, Li S, Zeng Z. The MTHFR C677T polymorphism contributes to increased risk of Alzheimer's disease: evidence based on 40 case-control studies. Neurosci Lett. 2015 Jan 23;586:36-42. Epub 2014 Dec 5 PubMed.

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Research Models

  1. Trem2 R47H KI x APOE4 (LOAD1)
  2. Mthfr*C677T/APOE4/Trem2*R47H