Rao A, Chen N, Kim MJ, Blumenfeld J, Yip O, Liang Z, Shostak D, Hao Y, Nelson MR, Koutsodendris N, Grone B, Ding L, Yoon SY, Arriola P, Zilberter M, Huang Y. Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimer's disease model. Cell Stem Cell. 2024 Oct 30; Epub 2024 Oct 30 PubMed.

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Mutations

  1. APOE Loss of Function Variants
  2. APOE C130R (ApoE4)