Although these data are preliminary, I think they are interesting. They suggest that non-coding variation is associated with risk for contraction of feedborne BSE. I can imagine that suitable control selection in cattle is tough, so this could certainly be a confound.
If correct (and if there is no coding variation in cis with the associated allele), this would presumably have a different mode of action than that associated with risk for CJD, where homozygosity of coding alleles appears to be important.
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National Institutes of Health
Although these data are preliminary, I think they are interesting. They suggest that non-coding variation is associated with risk for contraction of feedborne BSE. I can imagine that suitable control selection in cattle is tough, so this could certainly be a confound.
If correct (and if there is no coding variation in cis with the associated allele), this would presumably have a different mode of action than that associated with risk for CJD, where homozygosity of coding alleles appears to be important.
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