Nicolau C, Greferath R, Balaban TS, Lazarte JE, Hopkins RJ. A liposome-based therapeutic vaccine against beta -amyloid plaques on the pancreas of transgenic NORBA mice. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2332-7. PubMed.

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  1. I think this is a clever approach to producing a vaccine that would seem more cost-effective than the present Elan vaccine. While the
    authors claim that their vaccine is highly antigenic, it is hard to know
    how it would compare to the Elan vaccine without a direct comparison.
    Clearly this is another viable route to producing anti-Aβ antibodies
    in vivo.

    View all comments by Dave Morgan

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