Deane R, Sagare A, Hamm K, Parisi M, LaRue B, Guo H, Wu Z, Holtzman DM, Zlokovic BV. IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor. J Neurosci. 2005 Dec 14;25(50):11495-503. PubMed.

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  1. These reports all seem very interesting and important provided that amyloid has a primary and not a secondary role in neurodegeneration or even the reverse, a protective role. If so, could that explain the negative effect of active and now also of passive immunisation as reported by the John Trojanowski group?
    Alzforum is a truly great asset!

    View all comments by Arne Brun

  2. This has helped me very much, because I have a report for school and you gave me a lot of information. Thanks!

    View all comments by Theodore Muench

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