Benzow K, Karanjeet K, Oblak AL, Carter GW, Sasner M, Koob MD. Gene replacement-Alzheimer's disease (GR-AD): Modeling the genetics of human dementias in mice. Alzheimers Dement. 2024 Apr;20(4):3080-3087. Epub 2024 Feb 11 PubMed.

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Research Models

  1. MAPT(H1.0)-GR
  2. MAPT(H1.0*N279K)-GR
  3. MAPT(H2.1)-GR
  4. MAPT(H1.0*)P301L-GR
  5. MAPT 10IVS+16 C>T

Mutations

  1. MAPT P301L

News

  1. MODEL-AD Probably Has Something for You