. γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome. Ann Neurol. 2024 Aug;96(2):390-404. Epub 2024 May 15 PubMed.

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Mutations

  1. Trisomy 21