Hatami A, Monjazeb S, Milton S, Glabe CG. Familial Alzheimer's Disease Mutations within the Amyloid Precursor Protein Alter the Aggregation and Conformation of the Amyloid-β Peptide. J Biol Chem. 2017 Feb 24;292(8):3172-3185. Epub 2017 Jan 3 PubMed.

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Mutations

  1. APP E693del (Osaka)
  2. APP E693G (Arctic)
  3. APP E693Q (Dutch)
  4. APP D694N (Iowa)
  5. APP A673V