Tackenberg C, Kulic L, Nitsch RM. Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system. PLoS One. 2020;15(9):e0239584. Epub 2020 Sep 23 PubMed.

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Mutations

  1. APP E693del (Osaka)
  2. APP E693G (Arctic)