Thinakaran G, Harris CL, Ratovitski T, Davenport F, Slunt HH, Price DL, Borchelt DR, Sisodia SS. Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors. J Biol Chem. 1997 Nov 7;272(45):28415-22. PubMed.
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Osaka City University Medical School
PS1 and PS2 are currently hot tips in AD field and the relationship between the causal genes such as PS1, PS2 and APP must be interesting because they introduce the same neuropathology.
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