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Hansson O, Zetterberg H, Vanmechelen E, Vanderstichele H, Andreasson U, Londos E, Wallin A, Minthon L, Blennow K. Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment. Neurobiol Aging. 2010 Mar;31(3):357-67. Epub 2008 May 19 PubMed.
Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
---|---|---|---|---|
Aβ40 (Plasma) |
MCI-AD (15) |
162 ± 70 pg/mL |
xMAP; INNO-BIA Aβ Forms; Innogenetics |
McKhann et al., 1984 |
Aβ40 (Plasma) |
MCI-AD (48) |
208 ± 43 pg/mL |
xMAP; INNO-BIA Aβ Forms; Innogenetics |
McKhann et al., 1984 |
Aβ40 (Plasma) |
MCI-Stable (51) |
197 ± 38 pg/mL |
xMAP; INNO-BIA Aβ Forms; Innogenetics |
Petersen, 2004 |
Aβ40 (Plasma) |
MCI-Stable (88) |
160 ± 55 pg/mL |
xMAP; INNO-BIA Aβ Forms; Innogenetics |
Petersen, 2004 |
Aβ42 (Plasma) |
MCI-AD (15) |
24 ± 10 pg/mL |
xMAP; INNO-BIA Aβ Forms; Innogenetics |
McKhann et al., 1984 |
Aβ42 (Plasma) |
MCI-AD (48) |
31 ± 9 pg/mL |
xMAP; INNO-BIA Aβ Forms; Innogenetics |
McKhann et al., 1984 |
Aβ42 (Plasma) |
MCI-Stable (51) |
30 ± 9 pg/mL |
xMAP; INNO-BIA Aβ Forms; Innogenetics |
Petersen, 2004 |
Aβ42 (Plasma) |
MCI-Stable (88) |
27 ± 8 pg/mL |
xMAP; INNO-BIA Aβ Forms; Innogenetics |
Petersen, 2004 |
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