Salloway S, Ferris S, Kluger A, Goldman R, Griesing T, Kumar D, Richardson S, . Efficacy of donepezil in mild cognitive impairment: a randomized placebo-controlled trial. Neurology. 2004 Aug 24;63(4):651-7. PubMed.

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  1. This work implies that MCI treatment, which is more preventive in nature than that AD treatment, requries a strategy that targets pathological events upstream of cholinergic neuorodegeneration.

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Therapeutics

  1. Donepezil

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