Morishima-Kawashima M, Oshima N, Ogata H, Yamaguchi H, Yoshimura M, Sugihara S, Ihara Y. Effect of apolipoprotein E allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain. Am J Pathol. 2000 Dec;157(6):2093-9. PubMed.
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Osaka City University Medical School
ApoE4 is suggested to have a similar effect on Abeta42 as the early onset genes like PS1, PS2 or APP.
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