. Dopamine inhibits mitochondrial motility in hippocampal neurons. PLoS One. 2008;3(7):e2804. PubMed.

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  1. This study sheds light on the fact that mitochondrial dysfunction in disease can be initiated by impaired transport (such as of cargoes including mitochondria), in the absence of changes e.g. in mitochondrial complex I, II, III etc activities. It highlights a role for dopamine in mitochondrial motility and hence provides a link between PD and mitochondrial dysfunction.

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