Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed R, Liosatos M, Morgan TE, Rozovsky I, Trommer B, Viola KL, Wals P, Zhang C, Finch CE, Krafft GA, Klein WL. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci U S A. 1998 May 26;95(11):6448-53. PubMed.

Recommends

Please login to recommend the paper.

Comments

    • User Profile Image Hiroshi Mori
      Osaka City University Medical School
    • Posted:

    This paper shows some relationship between ADDLs and Fyn function in amyloid-derived toxic reaction. It may contribute to the molecular analysis of apoptosis in AD.

    View all comments by Hiroshi Mori

Make a Comment

To make a comment you must login or register.

This paper appears in the following:

News

  1. Immunotherapy Protects against Synaptic Effects of Soluble Amyloid-β Oligomers
  2. Playing "Gotcha" with the Phantom: α-synuclein Oligos Spotted in Vivo
  3. The Plot Thickens: The Complicated Relationship of Tau and Aβ
  4. SfN: Amyloid Oligomers—Not So Elusive, After All? Part 1
  5. Synaptic Plasticity Falters Early in AD Mice
  6. San Diego: Oligomers Live Up to Bad Reputation, Part 1
  7. Stable Aβ Oligomers?—A Little Protein Engineering Goes a Long Way
  8. Research Brief: Assessing Aβ Oligomers Toxicity in Live Mice
  9. Patient Aβ Dimers Sufficient for Tau, Neuritic Changes
  10. Tracing a Path from Aβ to Tau Leads Scientists to Lost Synapses
  11. Test Closes in on Oligomers, May Distinguish Alzheimer’s Patients From Controls
  12. Can Monkeys Model Alzheimer’s Better than Rodents?
  13. Aβ 'Receptors' Retard Fibrillization, Enhancing Toxicity

Webinars

  1. Clearing the Fog Around Aβ Oligomers

Research Timeline Event

  1. Oligomers reported as bioactive Aβ species