The role of the COX genes may be quite important in AD, not only from the point of view of an inflammatory cascade, but also in relation to synaptic activation. It would be of interest to determine whether the signal was neuronal, glial or both. Additionally, if beta-actin is reduced in AD through any of a variety of mechanisms, the data as corrected would be affected.
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Banner Research Institute
The role of the COX genes may be quite important in AD, not only from the point of view of an inflammatory cascade, but also in relation to synaptic activation. It would be of interest to determine whether the signal was neuronal, glial or both. Additionally, if beta-actin is reduced in AD through any of a variety of mechanisms, the data as corrected would be affected.
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