Buerger K, Teipel SJ, Zinkowski R, Blennow K, Arai H, Engel R, Hofmann-Kiefer K, McCulloch C, Ptok U, Heun R, Andreasen N, DeBernardis J, Kerkman D, Moeller H, Davies P, Hampel H. CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects. Neurology. 2002 Aug 27;59(4):627-9. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
tau-p231
(CSF)		 AD
(55)		 710 ± 373
pg/mL		 ELISA;
Other/Not Specified;
Molecular Geriatrics Corp.		 McKhann et al., 1984
tau-p231
(CSF)		 CTRL-
CNC
(30)		 78 ± 114
pg/mL		 ELISA;
Other/Not Specified;
Molecular Geriatrics Corp.
tau-total
(CSF)		 AD
(55)		 721 ± 352
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
tau-total
(CSF)		 CTRL-
CNC
(30)		 247 ± 137
pg/mL		 ELISA;
Innotest;
Innogenetics

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This paper appears in the following:

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  1. Translational Biomarkers in Alzheimer Disease Research, Part 5

AlzBiomarker

  1. AD vs CTRL : tau-p231 (CSF)
  2. CTRL vs AD : tau-p231 (CSF)
  3. AD vs CTRL : tau-total (CSF)
  4. CTRL vs AD : tau-total (CSF)