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Gordon MN, King DL, Diamond DM, Jantzen PT, Boyett KV, Hope CE, Hatcher JM, DiCarlo G, Gottschall WP, Morgan D, Arendash GW. Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 mice. Neurobiol Aging. 2001 May-Jun;22(3):377-85. PubMed.
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Massachusetts Institute of Technology
"This mouse model suggests a link between deposition of mAPP and mPS1 and cognitive impairment in transgenic mice, and suggests that one link may be deposition of Abeta in frontal cortex and hippocampus."
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