Mori T, Paris D, Town T, Rojiani AM, Sparks DL, Delledonne A, Crawford F, Abdullah LI, Humphrey JA, Dickson DW, Mullan MJ. Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APP(SW) mice. J Neuropathol Exp Neurol. 2001 Aug;60(8):778-85. PubMed.
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Boston University School of Medicine
"Increasing data implicates cholesterol in the pathophysiology of AD. This report examines the question from a neuropathological standpoint and shows a relationship between cholesterol and Ab deposition. However, it is possible that the significant link observed in the paper could be due to the association of apolipoprotein E and Ab , rather than cholesterol and Ab."
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