Andreasen N, Vanmechelen E, Van de Voorde A, Davidsson P, Hesse C, Tarvonen S, Räihä I, Sourander L, Winblad B, Blennow K. Cerebrospinal fluid tau protein as a biochemical marker for Alzheimer's disease: a community based follow up study. J Neurol Neurosurg Psychiatry. 1998 Mar;64(3):298-305. PubMed.
AlzBiomarker Database
Meta-Analysis
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| tau-total (CSF) |
AD (43) |
796 ± 382 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-total (CSF) |
CTRL- CNC (18) |
190 ± 57 pg/mL |
ELISA; Innotest; Innogenetics |
|
| tau-total (CSF) |
VaD (21) |
708 ± 382 pg/mL |
ELISA; Innotest; Innogenetics |
Román et al., 1993 |
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Comments
Osaka City University Medical School
Tau is a potent molecular maker for AD diagnosis but is not enough by itself. In any case, we need multiple observations of CSF-tau, such as the present paper.
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