Asante EA, Linehan JM, Desbruslais M, Joiner S, Gowland I, Wood AL, Welch J, Hill AF, Lloyd SE, Wadsworth JD, Collinge J. BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein. EMBO J. 2002 Dec 2;21(23):6358-66. PubMed.

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    • User Profile Image John Hardy
      Institute of Neurology, UCL
    • Posted:

    This is a very surprising finding which may suggest that the incidence of BSE-caused CJD is about twice what was thought... this is just over 100 people so far.

    View all comments by John Hardy

  2. This is an interesting study. To add to the horizon of prion diseasespathogenesis please do not miss recent Neurobiol Lipids article"The prion protein and cellular cholesterol homeostasis" [ FullText
    ].

    View all comments by Alexei Koudinov

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