Laird FM, Cai H, Savonenko AV, Farah MH, He K, Melnikova T, Wen H, Chiang HC, Xu G, Koliatsos VE, Borchelt DR, Price DL, Lee HK, Wong PC. BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions. J Neurosci. 2005 Dec 14;25(50):11693-709. PubMed.

Recommends

Please login to recommend the paper.

Comments

No Available Comments

Make a Comment

To make a comment you must login or register.

This paper appears in the following:

News

  1. Dual Secretase Approach Shows Promise in AD Mice
  2. BACE Knockouts Show More Synaptic Troubles
  3. In Conditional BACE1 Knockouts, Hippocampal Axons Compromised

Research Timeline Event

  1. BACE knockout mice have a phenotype, including premature death