Seuma M, Lehner B, Bolognesi B. An atlas of amyloid aggregation: the impact of substitutions, insertions, deletions and truncations on amyloid beta fibril nucleation. Nat Commun. 2022 Nov 18;13(1):7084. PubMed.

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Mutations

  1. APP E693del (Osaka)
  2. APP E693G (Arctic)
  3. APP A713T
  4. APP E682K (Leuven)
  5. APP L705V
  6. APP A673V
  7. APP D678H (Taiwanese)
  8. APP K687Q
  9. APP F690_V695del (Uppsala deletion)
  10. APP L688V (Greek)