Paper
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Hartman RE, Laurer H, Longhi L, Bales KR, Paul SM, McIntosh TK, Holtzman DM. Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease. J Neurosci. 2002 Dec 1;22(23):10083-7. PubMed.
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Comments
Another thorough analysis of the PDAPP mice from the Holtzman lab. If one believes the human data and inferences, then these results are predictable. But it is satisfying that the animal results are consistent with the human data.
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