Tomassen J, den Braber A, van der Lee SJ, Reus LM, Konijnenberg E, Carter SF, Yaqub M, van Berckel BN, Collij LE, Boomsma DI, de Geus EJ, Scheltens P, Herholz K, Tijms BM, Visser PJ. Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer's disease polygenic risk score. BMC Neurol. 2022 Dec 15;22(1):484. PubMed.

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Mutations

  1. APOE C130R (ApoE4)