Cairns NJ, Ikonomovic MD, Benzinger T, Storandt M, Fagan AM, Shah AR, Reinwald LT, Carter D, Felton A, Holtzman DM, Mintun MA, Klunk WE, Morris JC. Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report. Arch Neurol. 2009 Dec;66(12):1557-62. PubMed.

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  1. All these observations of amyloid deposition in prodromal AD clearly demonstrate that amyloidosis is an early marker of a pathological process that will lead to AD dementia. Accordingly, they also demonstrate that preamyloid, oligomer deposition has not this huge toxicity that makes hot headlines.

    View all comments by Andre Delacourte

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