Bossy-Wetzel E, Talantova MV, Lee WD, Schölzke MN, Harrop A, Mathews E, Götz T, Han J, Ellisman MH, Perkins GA, Lipton SA. Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels. Neuron. 2004 Feb 5;41(3):351-65. PubMed.

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  1. This is a very interesting finding in line with our publicaion. We have published already our finding on trace metal increase in moderately affected AD brain compared to control. In particular, we found that Zn was higher than other elements Si, Cu, Mg, Ca, Fe, Al , Fe, etc. However Fe, & Al was extremely elevated only in severe AD. Publiction is available In Alzeimr's Reports Vol 2, No. 4, 1999, pp 241-246.
    With regards,
    R.V.Rao & K.S.J.Rao et.al

    View all comments by Ranganath Rao

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  1. Nitric Oxide and Zinc—Conspirators in Cell Death