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Petit A, St George-Hyslop P, Fraser P, Checler F. Gamma-secretase-like cleavages of Notch and beta APP are mutually exclusive in human cells. Biochem Biophys Res Commun. 2002 Feb 8;290(5):1408-10. PubMed. Recommends Please login to recommend the paper. Comments Edward Koo Posted: 21 May 2002 I don't think this study argues for distinct proteolytic activities. One cannot saturate g-secretase activity by over-expressing APP. View all comments by Edward Koo Make a Comment To make a comment you must login or register.
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I don't think this study argues for distinct proteolytic activities. One cannot saturate g-secretase activity by over-expressing APP.
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