. Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice. J Neurochem. 1999 Jun;72(6):2479-87. PubMed.

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  1. Experimental animals enable us to study a mechanism for plaque formation from the soluble amyloid to insoluble amyloid. Little information [has been available for] distinguishing [the metabolism of] these two species. This study is one of the important works on the right track.

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