Clonality: monoclonal
Host: Mouse
Source: (Konrad Beyreuther, Center of Molecular Biology, University of Heidelberg, Heidelberg, Germany)
Paper
Reference:
Kuhn, 2010
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat

Immunogen/Epitope

immunogen = a bacterial APP fusion protein (Fd-APP 695),
(epitope in ectodomain, at residues 66-81 of APP)

Specificity

detects a variety of mature as well as immature APP species which differ in their degree of glycosylation

Comments / Questions

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References

Paper Citations

1. Kuhn PH, Wang H, Dislich B, Colombo A, Zeitschel U, Ellwart JW, Kremmer E, Rossner S, Lichtenthaler SF. ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons. EMBO J. 2010 Sep 1;29(17):3020-32. PubMed.

External Citations

1. Konrad Beyreuther
2. Paper

Further Reading

No Available Further Reading