Antibody

p70 S6 Kinase phos Thr389 (1A5)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2a
Source: Cell Signaling
Cat# 9206
Reference:
Boland, 2010
Formulation: liquid, protein-A and affinity purified, HEPES, saline, BSA, glycerol, azide
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat, Drosophila

Immunogen/Epitope

immunogen = synthetic phospho-peptide (KLH-coupled) corresponding to residues around Thr389 of human p70 S6 kinase

Specificity

detects endogenous levels of p70 S6 kinase only when phosphorylated at Thr389; also detects p85 S6 kinase when phosphor. at the analogous site (Thr412) and possibly S6KII phosphor. at Thr401

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References

Paper Citations

  1. Boland B, Smith DA, Mooney D, Jung SS, Walsh DM, Platt FM. Macroautophagy is not directly involved in the metabolism of amyloid precursor protein. J Biol Chem. 2010 Nov 26;285(48):37415-26. PubMed.

Further Reading

No Available Further Reading