Antibody
α-Synuclein
Quick Links
Clonality: monoclonal
Host: Mouse
Source: α-Synuclein nSyn823
(Virginia Lee, University of Pennsylvania, CNDR, Philadelphia, PA)
used in paper by Giasson, 2002
Reactivity:
reference:<br />Giasson BI. Duda JE. Murray IV. ... Lee V.M.-Y. Science., 290:985-989, 2000
Immunogen/Epitope
immunogen = nitrated α-synuclein
Specificity
nitration specific α-synuclein
References
Paper Citations
- Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VM. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron. 2002 May 16;34(4):521-33. PubMed.
External Citations
Further Reading
News
- Fatal Attraction or Beneficial Interaction: Microglia, Aβ and Neurons
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- Clearing Aggregates—Macrophages Fall Short for Aβ, but Vaccine Mops Up α-synuclein
- Microglia—Medics or Meddlers in Dementia
- DC: New Neprilysin Methods Reduce Brain Aβ
- DC: Aβ Clearance—Roles for MBP, Transcription Factors?
- The Brain and Microglial Recruitment—Think Local, Not Global
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